Exact(4)
Also, our study is based on more recent metabolic datasets, with a larger set of taxa.
More recent metabolic models have been built accounting for additional regulatory [ 19] and metabolic components (e.g. glutathione [ 20]).
As explained in the section Conclusion and Outlook, the results of this study motivate us to perform a large scale study with more recent metabolic networks.
The more recent metabolic syndrome definition by the International Diabetes Federation sets ethnicity specific criteria for waist circumference to define central obesity in adults, with cutoff points equal to 80 and 94 cm for Caucasian women and men, respectively (11).
Similar(56)
Because not all known human metabolic pathways are included in HumanCyc and KEGG, we also considered a more recent human metabolic network, manually reconstructed by integrating genome annotation information from different databases and metabolic reaction information from specialist literature [38].
In this study we investigated the relationships between physical activity and three of the more recent markers of metabolic disturbance using an objective measure of physical activity whose reliability was optimized by a longitudinal design.
Although NAFLD is known as the hepatic manifestation of IR or metabolic syndrome, more recent reports have suggested that subjects with NAFLD are at increased risk for CAD independent of metabolic syndrome and insulin resistance [ 33, 34].
More recent research indicates that the metabolic cost of locomotion is made up of a number of components.
Our data, obtained through a novel analysis methodology, strongly supports the hypothesis that the patchwork model better explains the more recent evolution of the S. cerevisiae metabolic network.
Finally, with respect to treatment, the more recent data on the mechanisms through which metabolic surgery may favor remission of diabetes are also discussed.
More recent phenotyping projects have included measuring basal metabolic rate, personality [ 21], malarial infection and social network data for small subsets of individuals (Sheldon, unpublished data).
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