Of the few lncRNA mutant mice generated to date, most involved previously studied and classic examples of lncRNAs (e.g., Xist, H19, Kcn11ot1, Malat1) (Anguera et al., 2011; Gomez et al., 2013; Gordon et al., 2010; Moseley et al., 2006; Nakagawa et al., 2011; Ripoche et al., 1997; Zhang et al., 2012), leaving the more recent large-scale RNA-Seq-derived catalogs of lincRNAs largely unexplored.
Mr. Michel oversaw the firm's work on more recent large-scale transportation projects, like Atlanta's rapid transit system, the first Caracas Metro line in Venezuela and the transit system of Taipei, Taiwan.
The sounds of invisible dancers thumping around an empty floor in his choreography for an exhibition about the influence of Marcel Duchamp at London's Barbican in 2013, in his more recent large-scale interventions at Paris's Palais de Tokyo, in Milan and at New York's Park Avenue Armory.
A more recent large-scale 16S rRNA sequencing effort identified 128 phylotypes from 8 phyla in 23 North American patients [16].
More recent large-scale studies and analyses have investigated the influence of latitude on diversity, most notably Rex et al. [102] [104] looking at deep-sea bivalves, gastropods, and isopods and Gage et al. [105] looking at Cumacea in the deep Atlantic.
These findings have been verified in more recent, large-scale GWAS in different populations [13]– [15].
Another more recent large-scale public health intervention occurred that targeted all age groups.
A more recent large-scale study included 13,472 women also failed to show an increased risk of contralateral breast cancer for those received radiotherapy [ 37].
Two more recent large-scale trials could not replicate the initial promising findings from Belgium and reported higher complication rates within the tight glucose control group (51, 52).
For confirmation, the differential TNFSF4 expression was checked in LN compared with healthy controls using publically available data from a more recent large-scale genome-wide gene-expression analysis conducted in renal biopsies [ 9].
