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Broader entry criteria will make trial results more generalizable and will result in more rapid trial accrual.
This approach can enable more rapid trial closure or acceleration than trials focusing on a specific disease site, depending upon patient response rates, and could permit FDA consideration of a drug for approval in multiple disease sites [ 20].
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Ultimately, it will lead to richer sources of support for clinical trials and more rapid trials.
For LA, we found a significant main effect of group, F (1, 78) = 8.31, p =.005, η p = 0.10, with aMCI patients showing more rapid forgetting between trials.
COMP is going to be helpful in selecting patients at high risk for cartilage loss for recruitment into clinical trials: more rapid assessment of the efficacy of a disease-modifying drug will be possible, and anything that helps facilitate clinical trials is a good thing.
The DNA Vaccines meeting of 2008 suggests that we may see more rapid advances in clinical trials, with the Holy Grail being a successful DNA vaccine in the not too distant future.
Therefore it is not so predictable whether the Rolling 6 will result in more rapid completion of a single trial or of a small series of trials.
The findings reported here from a trial comparing a new, more rapid and discriminatory typing test (MLVA) with slower PCR-ribotyping help to address some of these questions.
Thus, the information gained from neoadjuvant testing is invaluable, and for the purpose of this review it represents excellent in vivo confirmation of effects of new agents allowing a more rapid start of large adjuvant trials.
Concepts that didn't work were quickly abandoned and other more effective modes were identified by rapid trial and error.
Thus, from the experimental point of view, delay conditioning has the advantage of a shorter acquisition time, fewer trials, and a more rapid conditioning process than trace conditioning.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com