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Prosecutors in the case, who had sought about 70 days before a trial, said that a more rapid schedule was unheard-of in a complex corporate investigation that would rely on the testimony of dozens of witnesses.
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Concerning more rapid injection schedules, one study [ 68] compared blood pressure changes and adverse events between 36 patients infused at a rate of 3 mg/kg/min up to a maximum dose of 15 mg/kg, 24 patients infused at 3 mg/kg/min up to 30 mg/kg, and six patients infused at 6 mg/kg/min up to 15 mg/kg.
Accordingly, high dosage, short-course therapy regimens with a once daily administration schedule may yield more rapid bacterial killing or prevention of resistance development [ 36- 38].
In the treatment of acute manic episodes, simplified dosing and a faster titration schedule may result in more rapid improvement, which might be expected to lead to a shorter duration of hospital stay.
A recent study found that feeding on a schedule was associated with more rapid weight gain (Mihrshahi et al., 2011), which the authors suggested could be due to overriding the infant's ability to self-regulate.
Lastly, high-dosage, short-course therapy regimens with concentration-dependent antibiotics through a once-daily administration schedule may yield a more rapid bacterial killing or prevention of resistance development.
Orsolini and Goldfarb reported more rapid and comparatively high seroprotection rates with the conventional schedule in neonates [ 5, 6].
Compared with other doses and schedules tested, this regimen is associated with more rapid haematological recovery; an improved AE profile, including decreased rates of aggregated sepsis and infections; and low 30- and 60-d all-cause mortality.
All these factors together can lead to an irregular publication schedule, which with the perception that publication in Northern Hemisphere journals will facilitate more rapid career development can deter local scientists and clinicians from publishing in their national journals.
"They are more rapid.
But Ford is making more rapid progress.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com