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Both strains showed more rapid clearance during ventilation with 10 cmH2O PEEP compared with other ventilation pressures (p < 0.001).
Another explanation for the more rapid clearance could be a higher amount of aggregation of 125I-Fab than for 111In-Fab [31], resulting in an increase in the effective size and, thus, clearance from the circulation via a size-dependent mechanism, as has been shown previously for liposomes [40].
Experience gained from cidofovir-induced uveitis and hypotony indicates that toxicity to the nonpigmented epithelium of the ciliary body is uncommon after intravitreal therapy [8] compared to systemic administration [9], an effect that may be due to the more rapid clearance of intravitreally administered drug compared to recirculation from a serum depot.
Huang et al.[14] studied the effect of uncoated and PEGylated MSNs with two different ARs (1.5 and 5) on biodistribution, clearance and biocompatibility in vivo, whereby they found that the AR affected the clearance rate in that short rod MSNs (AR ~ 1.5) had a more rapid clearance rate than the long rod MSNs (AR ~ 5).
Therefore to achieve more rapid clearance of mosquito-infective stages from the blood stream an actively gametocytocidal drug may be required [13].
Although immunization with Hia reduced bacterial load in our model comparable to D15 and AfuA, it failed to induce more rapid clearance.
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Interestingly, females displayed more rapid ethanol clearance than males and there were no effects of either diet or wheel access on clearance rates.
Tc-99m-tetrofosmin or better Tc-99m-N-DBODC5 has a more rapid liver clearance than Tc-99m-sestamibi [21, 22].
In the present study, we hypothesized that coronary occlusion followed by reperfusion would lead to more rapid myocardial clearance of Tc-99m-teboroxime due to myocyte membrane damage resulting from both ischemia and reperfusion injury.
The corresponding digital analysis (Figures 6A and 6B) show much more rapid blood clearance and specific uptake in CAIX rich regions.
We tested the hypothesis that environmental enrichment leads to less CNS neuroinvasion and/or more rapid viral clearance in association with T cells without neuronal damage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com