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The classes can then be related to psychopathology outcomes, or other more proximal risk factors on the pathway to later psychiatric disorders.
Neurocognitive impairments may therefore represent a common or distal risk factor whose influence on violence is mediated by a range of more proximal risk factors.
Thus, early adversity appears to set in action a chaining of effects that increase the likelihood of more proximal risk factors in adolescent girls.
When the influence of neurocognition on violence was explored using mediation analysis, neurocognition emerged as a distal risk factor whose effect on violence occurred through more proximal risk factors.
Neurocognition therefore appears to be a distal risk factor for violence whose influence only becomes manifest through more proximal risk factors such as social cognition, symptoms, functioning and the risk factors contained within the HCR-20.
However, other causal relationships need to be considered since maternal drinking may be correlated with parental behaviours that could act as more proximal risk factors, such as levels of critical comments, quality of parenting and maternal psychopathology including ADHD.
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However, identifying more proximal risks did not always promote greater message acceptance among participants.
By examining how different measures of socioeconomic position are associated with the risk of spontaneous abortion, we might be able to come closer to identification of more proximal causal risk factors for spontaneous abortion.
Nevertheless ascertaining such indicators of risk may be advantageous when identifying high risk subgroups of ADHD children, as well as providing a starting point for research attempting to find more proximal, causal risk factors.
Similar results are found in research conducted among young, urban MSM (55), where psychosocial health problems (such as binge drinking, drug use, and interpersonal violence) were found to have additive effects on the odds of HIV positive status and on more proximal sexual risk behaviors, including multiple anal sex partners and unprotected anal sex.
While education measures socioeconomic status closer to the time of reproductive choices which are important for breast cancer risk, more proximal exposures such as post menopausal obesity, screening, and HT use are also important for breast cancer risk and so both measures are relevant.
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