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Not surprisingly, both sets are enriched in development-associated biological process terms, but multi-only has more proteins involved in cell recognition and glucose homeostasis (Fig. 4a).
These interactions may form the basis for rational design of small peptide mimics of one or more proteins involved in order to inhibit protein protein interactions and thus transcription.
Is one or more proteins involved in the formation of metal clusters?
It is therefore important to identify more proteins involved in T. brucei motility.
At one level this indicates that one or more proteins involved in SOCE are degraded by the proteasome in response to store-depletion.
When more proteins involved in a common biological role harbor an accessible cleavage site for the protease and share the subcellular loci (and cell type and tissue distribution), then, it is reasonable to assume a role for the protease in modulating such a biological function.
Similar(48)
Curiously, this genomic locus encoded in K. pneumoniae at least one more protein involved in anaerobic metabolism, the anaerobic C4-dicarboxylate transporter DcuA (KpST66_4904), supporting the idea that this GI provides K. pneumoniae advantages to grow under anaerobic conditions, possibly favoring infection.
In unfit but otherwise healthy middle-aged adults, two weeks of modified HIIT training prompted the creation of far more cellular proteins involved in energy production and oxygen.
This suggests that the drug affected one or more parasite proteins involved in motility but unrelated to microneme secretion.
For all the organisms we compared, there were two- to three-fold more predicted proteins involved in 1CST systems than in 2CST systems (Table S7) (the only exception being B. petrii that has a slightly higher preference for 1CST systems).
However, there are certainly more signaling proteins involved in this process, such as PKC-δ mentioned above [ 47].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com