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However, in contrast to what might be expected, they are not major components of, but are only focally and variably expressed in squamous cell carcinomas of the head and neck, with more pronounced expression in poorly differentiated cases (Moll 1998).
This may be a consequence of the more pronounced expression of hydrological loading in the Negro and Solimões river confluence region.
RT-PCR results support a more pronounced expression of rupsA2-type variants than rupsA1 or any other type in asexual and immature sexual stages, indicating differential regulation of the two gene clusters.
Interestingly, although we noticed a more pronounced expression of TGF-β mRNA in animals subjected only to UUO, when compared to Hemin-treated animals, there was no statistical difference (Figure 6E).
Concomitant administration of EcN to DSS treated animals resulted in a significant protection against intestinal barrier dysfunction and IECs isolated from these mice exhibited a more pronounced expression of ZO-1.
Positive values indicate lower expression in RA SFBs, and negative values show more pronounced expression in RA SFBs.
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However, samples showing more pronounced SOX2 expression levels (sample 1, 3 and 10) displayed substantial co-expression of OCT4 and NANOG.
Our xenograft model showing more pronounced GLUT1 expression and pimonidazole uptake within perinecrotic regions, and ATF3, ATF4, and HIF1 α expressions throughout the xenografts are in agreement with previous studies of patient tumours showing that GLUT1 expression was mainly perinecrotic and did not coincide with HIF1 α distribution (Sobhanifar et al, 2005; Vleugel et al, 2005; Tan et al, 2009).
Compared to naked PCL scaffolds, embedded scaffolds provided a higher cell seeding efficiency (t-test, P < 0.05), a more homogeneous cell distribution and more osteogenically differentiated cells, verified by a more pronounced gene expression of the bone markers alkaline phosphatase, osteocalcin, bone sialoprotein I and bone sialoprotein II.
Interestingly, the classes of genes enriched in p27Kip1 null tumors were similar to those enriched in tumors in general (Figure 3A,B and Table S2), suggesting that the p27Kip1 null tumors had a more pronounced lymphoma expression phenotype.
Surprisingly, unlike PR48 [ 20], hPR70 has a more pronounced cytoplasmic expression (CP >> N).
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Justyna Jupowicz-Kozak
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