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The same total amount of calcium (# 600 mg) from one liter of high-calcium mineral water, divided into three intakes, at 3 hours intervals, resulted in a more prolonged suppression of serum CTX, than from the ingestion of a calcium salt.
Old animals show more prolonged suppression of PG synthesis after IL-1 exposure than young mice [ 4] and display a reduced response to counteraction of IL-1 by TGF-beta [ 20].
The combined results from both experiments indicate that treatment with a dose-intense temozolomide schedule results in more prolonged suppression of MGMT activity than a standard dose schedule, but activity quickly returns after cessation of daily treatment.
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Similarly, in the current study, there were no remarkable differences between the clinical and molecular effects of two preparations with the exception that IVIgG treatment exerted a more pronounced and prolonged suppression effect on cerebral C5a receptor expression than IVIgGAM treatment.
The irreversible inhibition of multiple ErbB family receptors by afatinib results in more potent and prolonged suppression of receptor kinase activity compared with reversible first-generation EGFR-TKIs [ 31, 59, 61].
However, it seems that its response to trauma, burns, hemorrhagic shock, and microbial infection is associated with only a transient proinflammatory period followed by a more prolonged period of immune suppression [ 11].
Thus, the possibility remains that synergy between QMP and eβ on suppression of worker reproduction could occur in more prolonged experiments, with eβ suppressing OA and QMP stopping egg laying, although no significant differences or trends were evident between eβ+/QMP− and eβ+/QMP+ at 10 days.
Consistent with this hypothesis, a study reported in abstract form found that metastatic CRPC patients who had early development of castration resistance (<12 months) had a shorter TTP and shorter OS compared to patients with <span class="lh">more prolonged sensitivity to androgen axis suppression.
Similarly, they showed a more prolonged fever and a delayed recovery from LPS-induced suppression of social interaction.
20 Two dipeptidyl peptidase-4 (DPP-4) inhibitors (sitagliptin and saxagliptin) are approved in the US and inhibit the enzyme that metabolizes endogenous glucagon-like peptide-1; thus, this hormone has a more prolonged effect on postprandial glucose through its effects on insulin secretion and suppression of glucagon secretion.
Wong, J. K. et al. Recovery of Replication-Competent HIV Despite Prolonged Suppression of Plasma Viremia.
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