Sentence examples for more prolonged hypoxia from inspiring English sources

During more prolonged hypoxia (hours), dynamic cerebral autoregulation has nevertheless been found to be impaired, despite hypocapnia-mediated cerebral vasoconstriction [ 29].

Experiments looking at the effect of hypoxia on endothelial cells have predominately been concerning more prolonged hypoxic exposure (48 hours).

More recently, Elbarghati and colleagues have shown the regulation of both HIF-1 and HIF-2 by hypoxia in human monocyte-derived macrophages [ 16], and postulated the enhanced stability of HIF-2 over HIF-1 in the context of more prolonged hypoxic exposure.

The reduction of HIF-1 α stabilisation in response to treatment with VE-821 was also noted during more prolonged periods of hypoxia up to 18 h (Supplementary Figure S6C).

This rise in PVR in response to global hypoxia appears to be supported by a similar study by Dorrington et al. in which 6 healthy volunteers received a more prolonged period of global hypoxia 5 8 hours in a hyperbaric chamber, measuring pulmonary vascular resistance (PVR) in a more invasive fashion utilising a pulmonary artery catheter [ 41].

It might be that Glut-1 expression reflects more severe and longer duration hypoxia, especially as in our study intense staining (score 3) showed the best correlation with outcome and heavy staining is more indicative of de novo Glut-1 synthesis which only occurs after prolonged hypoxia (Shetty et al, 1992; Behrooz et al, 1997).

In addition, though severe or prolonged hypoxia initiates apoptosis, some cells adapt to hypoxia, survive and gain a more aggressive phenotype (Greijer and van der Wall, 2004).

Using this system, we generated T98G-DDS10 cexposedposed to 10 or more cycles of hypoxia and nutrient deprivation stress cycles, because most cancer cells including T98G cells cannot be maintained under the prolonged hypoxia and nutrient starvation DDS for longer than 72 h in vitro.

That could result in a much deeper, more prolonged downturn.

Prolonged hypoxia (5 km for 5 days) exposure augmented a 2.5-fold SS mRNA (p<0.001).

We hypothesized that fetal swallowing and intramembranous absorption would increase with prolonged hypoxia to offset the polyuria.