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These cases require a more prolonged course of antimicrobials following the surgical procedure.
However, some patients had more prolonged course of the disease, and in one of these cases A. baumannii-associated death occurred 52 days after the diagnosis of infection.
Mostly a mild disorder in childhood, varicella develops with a more prolonged course, and more severe complications and more disabling symptoms in adults., Therefore, the severity of varicella hospitalizations increases with age.
Illness recurred in 2 patients but resolved after a subsequent and more prolonged course of antimicrobial drug treatment (the 2 latter patients have been included in previous reports [ 7– 9]).
Virulence factors could also be measured, particularly for S. pneumoniae, Staphylococcus aureus, and Pseudomonas aeruginosa, to determine whether antibiotic therapy is actually needed in the first place, or whether the patient may benefit from either a more limited or more prolonged course of treatment.
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Sometimes relapses and more prolonged courses of illness are described [ 69].
In view of the high mortality rate in severe sepsis, clinicians believe themselves to "be on the safer side" with more prolonged courses of antimicrobial treatment.
Clinically, TP53-defective CLL is more aggressive, whereas ATM-defective CLL has a more prolonged clinical course.
However, the transferred T cells enhanced the CII-antibody-induced arthritis into a more prolonged disease course.
Patients who received heart transplants were significantly younger (mean age at the time of first symptoms 24±13 years) and had a more prolonged clinical course (time from first symptoms to transplant ≈15 years) compared with other ARVC/D registry participants.
Possible benefits conveyed by one sedative regimen over another may become evident over a more prolonged time-course as both IL-6 and apoptosis were reduced by dexmedetomidine but not midazolam.
More suggestions(15)
more severe course
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