Sentence examples for more proliferative cells from inspiring English sources
The increasing abundance of APC along the crypt axis forms a gradient of cellular adhesion that causes more proliferative cells to accelerate their movement toward the top of the crypt, where they are shed into the lumen.
Poorly differentiated tumors which are less differentiated contain more proliferative cells, and hence have higher CTIP2 expression.
We speculated that this difference was caused by different cell cycle rates among individual cells, such that biotin-labeled membrane proteins had been diluted to a larger extent in more proliferative cells.
Consequently, this higher level of EGF expression accelerated the restoration of epithelial integrity in the injured intestines, with more proliferative cells within the crypts.
Moreover, Ki67 staining showed that miR-587 tumors have slightly more proliferative cells than vector tumors in the absence of 5-FU, which may partially explain the small increase of growth rate of miR-587 tumors.
Overall, there were more proliferative cells in the muscle layers of KO than WT mice at the specified time points; particularly, there was a significant increase in cellular proliferation at KO PT21.
It is preferred to use the neonatal mice (1-2 days old), as our previous observations for cardiomyocytes have shown that younger animals (newborn up to 1-2 days) produce more proliferative cell cultures enrichment [ 18].
In agreement with the presence of more proliferative GFAP+ cells, the SEZ of young SAMP8 mice yielded more primary neurospheres when individual cells were plated with EGF and FGF (Fig. 3A– C).
These cells, being adjacent to the tip cell, take on the more proliferative stalk cell phenotype.
Also, p21Waf1/CIP1 depleted cells were more proliferative than control cells as measured by BrdU uptake and a significant number of these cells remained BrdU positive 48 hours after differentiation induced by calcium treatment (Figure 5C).
From studies of prostate cancer [45], ANXA2 upregulation is expected since in vitro experiments indicate that overexpression promotes a more invasive, proliferative cell phenotype.
