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However, active human NMO lesions contain CD4+ T-lymphocytes expressing the activation marker Ox40, and the expression is more profound compared to that seen in MS lesions of comparable activity.
The decrease in cytokine levels was significantly more profound compared to the moderate suppression of macrophage recruitment.
The present data also showed that the effect of protons on gene expression was more profound compared to photons.
For GOS/FOS and GOS/FOS/AOS, all effects on TNF-α production were significantly more profound compared to the effects of corresponding glucose/lactose controls.
The marked changes from a contractile to a synthetic and proliferative phenotype, the digestion of the internal elastic lamina and the digestion of the extra-cellular matrix, which allows motility are much more profound compared to the mild morphological changes that characterize the endothelium [ 117, 122, 129].
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The canonical regression analysis indicated that the pH had more profound effect compared with the starch level, in terms of the acid productions, enzyme activity and gene expressions.
The corresponding results for the DOMOTICA-3 database are depicted in the lower panel of Figure 5, displaying a positive, though, non-significant statistical tendency in favour of the compositional frame structure, i.e. the more profound structure compared to the flat one.
However, the differences where profound when we compared progressing sites at baseline with the breakdown time point and even more profound when we compared the two baseline samples from progressing and non-progressing sites.
In the modelling network, regional inequalities are much more profound even when compared to the 1971 network; see Table 3.
The fact that the downregulation of cytokine production to PPD as a result of OPV vaccination was more profound in LBW compared to NBW infants might be due to functional immaturity of LBW infants.
We speculated that infants with a disproportionate largeness (D-LGA) had been subjected to a more profound fetal hyperinsulinemia compared with infants who are proportionally large (P-LGA).
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