However, comparison becomes more problematical for a synthesis reaction in non-aqueous media where the free enzyme is not soluble.
Jerome Robbins's "I'm Old Fashioned" is more problematical.
The second and third reports could be more problematical for Hillary Rodham Clinton.
Their incompetence was made more problematical because the overall quality of the fiction in the year in question was poor.
The back room is more problematical, but its wall legends seem to refer to ways and properties of art materials.
More problematical, he said, was his frustration over a growing public perception that gun makers were "merchants of death" rather than part of a $6 billion sporting industry.
This is even more problematical as humanitarian agencies are simply not equipped for this role and have to rely on the authorities.
"The investment grade was premature," he said, "and the explanations given are exceedingly rosy, unreflective of a far more problematical situation".
More problematical is the possibility that more workers -- millions, according to pro-labor analysts -- could be forced into unpaid overtime under the regulations, which do not affect blue-collar or union-contract workers.
Passage in the Senate is somewhat more problematical since the measure contained an amendment raising the ceiling that Congress could approve for discretionary spending to $637 billion, from the current $600 billion.
