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Secondary prevention in patients with a history of one or more previous fragility fractures at major sites (hip or spine) or at minor sites plus T-score < − 3.
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Indeed, the presence of one or more prevalent vertebral fractures and/or other previous fragility fractures increases the relative risk of additional fragility fractures in the following year.
In both sexes, a previous fragility fracture is an important risk factor for further fractures.
Osteoporosis combined with previous fragility fracture is defined as established osteoporosis.
Exclusion criteria were: contraindications for steroidal therapy, including uncontrolled diabetes and previous fragility osteoporotic fractures.
Previous fragility fracture sites were classified as hip, vertebral, wrist, and other.
48 The risk of hip fractures increase substantially if there is a history of previous fragility fractures.
The valuation begins with a clinical situation to show the risk factors for osteoporosi's disease: the risk of falls and the previous fragility fractures in particular.
Thus, there is an urgent need for more accurate fragility data.
Using a statistical approach based on a logit formulation, a shift towards more robust fragility functions can be achieved.
More frequent fragility of all studies in sub-scale of bias was no attempting to blind the subjects and those who were measuring the outcomes to the exposures.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com