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Arthritis is a far more prevalent condition among women than among men [ 6- 10].
It is also a far more prevalent condition among women than men.
Asthma, a more prevalent condition, is referred to as 'lelah' meaning breathlessness, which is also a common presenting complaint in COPD.
For example, onabotulinumtoxinA (Botox, Allergan, Coolock, Dublin, Ireland), which received orphan drug designation for its initially approved indications, was approved in 2013 for treatment of overactive bladder, a far more prevalent condition.
Although the prevalence of ACAs is 20 to 40% in SSc and only 3to5%5% in SLE, it has been suggested that numerically more patients with ACAs would actually suffer from SLE than from SSc because SLE is a much more prevalent condition than SSc.
For example, Swedish annual primary and secondary care prevalence of psoriatic arthritis is twice that for England, but the absolute difference is low (eight extra people consulting per 10 000), whereas for a more prevalent condition like low back pain, a similar relative ratio constitutes a larger absolute difference (293 extra people consulting in England per 10 000).
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"Furthermore, if this is the case, can modulating this same pathway be a route to new therapeutic approaches in these more prevalent conditions that afflict many millions of sufferers around the world?
First approved for a rare blood condition called hairy cell leukemia for which it is now seldom used Roferon-A was later foused Roferon-Active for a number of other far more prevalent conditions, including chronic hepatitis C and chronic myelogenous leukemia.
As a result, physicians gravitate toward the more prevalent conditions first as the possible causes and look for factual data in test results to rule those in or out.
With apologies to research professionals that I admire, trust, and will always support (Simons Foundation, OAR, my geologist step-father), and with the acknowledgement that, compared with more prevalent conditions, autism research is dramatically under-funded, the autism research community has fallen into a slippery slope -- an ethical limbo wherein the money is high and the ideas are low.
The management of these more prevalent conditions may displace the focus on NVAF.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com