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The active disease is characterized by gluten-dependent auto-antibodies against endomysium and, more precisely, protein type 2 ('tissue') transglutaminase, the celiac autoantigen anchored to endomysial collagen by fibronectin [ 2, 3].
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More precisely, each protein has been associated to a binary feature vector, representing a protein profile, whose elements are 1 when the protein is annotated for a specific feature (e.g. includes a specific domain, or a specific motif), or 0 otherwise (second phase in Figure 5).
The first was to use network analysis to elucidate the topological importance of house-keeping and tissue-specific genes (or, more precisely, their protein products) in human PPI networks by asking whether proteins encoded by house-keeping genes or tissue-specific genes tend to occupy topologically important positions or not.
This study highlights how measurements of labile Zn2+ levels in live cells can be coupled with other cellular experiments to more precisely define protein functions.
More precisely, each protein is defined as being either active (value 1) or inactive (value 0) depending on its abundance or activity level.
More precisely, all proteins sequences are first clustered into groups by the Inparanoid algorithm (Brein et al., 2005), and only proteins from the same cluster can be considered as protein functional orthologs.
The fractions containing the ZZ-IGF-1 protein were pooled and the protein concentration was determined spectrophotometrically by comparison of the OD260/280 nm ratio, or more precisely by Bradford protein assay.
For the mean ODE approach variability is measured by the posterior standard error of the fit similar to a regression and the graph shows that predictions can be made more precisely about the protein dynamics than about the native mRNA.
Although the abundance and half-lives of methylated proteins could be analysed more precisely by comparing methylated proteins to other proteins from the same GO slim biological process, this approach was limited by the relatively small number of methylated proteins (66 proteins) in the dataset.
Or, more precisely, it's proteins in the droppings of the beings who dwell in debris that set off the allergies that accompany our annual winter-coat de-cupboarding.
If the set is not unique, we may more precisely define hub proteins as those whose neighbor coexpression distribution is maximally bimodal.
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