In order to determine more precisely a functional link between these two proteins in relation to their respective roles in the control of sexual dimorphism, we expressed both hmgcr (using UAS-clb) and UAS-RNAi-InR under the control of the DI-3 driver.
Our next aim was to further minimize the promoter and characterize more precisely its functional elements.
More precisely, integrating functional information available from different species and phylogenetic history allows making predictions on the ancestral as well as present day protein functions [ 47, 48].
More precisely, the functional classes E, F and P were significantly higher in H3+ (p < 1.8 × 10-3, 1.9 × 10-2 and 5.5 × 10-3, respectively), while G and Q showed opposite trend (p < 1.7 × 10-2 and 3.5 × 10-2, respectively).
In this article, we shall consider the symmetry given by a ℤ2 action, more precisely even functionals.
Genetic engineering has emerged as a method with high potential to modify traits more precisely and enable functional genomics studies more efficiently.
Fine-mapping of these segments is necessary to more precisely identify the functional candidate genes.
Correlative analysis of gene expression in the brain more precisely defined specific functional units than based on classical morphological markers (31).
Instead of deleting Cblb, we designed a more prudent strategy to specifically disrupt the NurRE region in the endogenous Cbl-b promoter using CRISPR/Cas9 genome editing tool, thus more precisely dissecting the functional interaction among Nur77, Cbl-b, and NFATc1.
More precisely, we defined functional classes as important for viruses using a larger comparative data set including cellular organisms from all branches of life for a total of 740,842 sequences (supplementary table S1, Supplementary Material online).
