Quality control studies have shown that results from RT-PCR are in agreement with microarray for genes with medium and high expression, and is not substantially more precise than the array platform employed itself [ 25].
After achieving the 2D RGD nano-dot, further approaches were undertaken for more precise RGD nano structure-array suitable for in vitro biological activity experiments similar to the in vivo condition [11].
However, it has been demonstrated that in S. cerevisiae, tiling arrays are more precise for determining the transcriptome structure [ 10].
In addition, the use of larger numbers of smaller probes on oligonucleotide arrays permits more precise delineation of the breakpoints of CNVs that are detected, which facilitates genotype-phenotype correlation and clinical interpretation.
The whole-transcriptome amplification protocol and probe design of exon arrays allow a more precise monitoring of such overall gene expression indexes.
Our findings suggest that the use of high-density oligonucleotide arrays may allow more precise boundary information to be extracted for CNV detection.
Additionally, full SNP annotation will inform future SNP array chips allowing for more precise genotyping.
Reduced array variance should mean more precise estimates of allele frequency, which should further minimize the loss of power associated with using the DNA pooling strategy.
The advent of SNP arrays offered improved resolution, enabling more precise mapping of copy number alterations and the detection of uniparental disomy (copy neutral loss of heterozygosity) as well as the ability to distinguish alleles at specific polymorphic sites [ 64– 64].
Research efforts using a broad array of methods resulted in a more precise understanding of the disease process that led again to the inclusion of uterine adenomyosis into the pathophysiology of endometriosis [ 8].
