Although the BALAD-2p model builds on the BALAD model's concept by including the ability to predict patient-level survival and as such is a more powerful prognostic device, validation in other regions of the world, especially where the aetiology is related to Hepatitis B, is still required.
We had to decide whether we were going to use modern statistical techniques like multiple imputation to replace missing values in order to create less biased estimates of accuracy and obtain more powerful sample sizes for external validation (Vergouwe et al, 2010).
Finally graphical representations of randomized quantile residuals are powerful validation tools that provide more detailed information about model characteristics than just comparing global statistics.
However, the original 25 years power plan has proved to be quite accurate in its social and economic previsions, and allows the validation of a new, more powerful and reliable planning model.
Finally, a third goal is to test the relative power of the theoretically expected more powerful protocol ("Protocol II", that employs balanced repeated 10-fold cross-validation estimator with AUC as the error metric and SVMs as classifier).
New information on risk based on genotype, mammographic density [ 13], and serum hormone levels [ 18, 53] should now allow a much more powerful prediction of risk for an individual woman – development and validation of these models is critical.
Great advances have been made in techniques for high-throughput epitope validation [ 13, 14], but as computational methods grow ever more powerful, so does the need for post-analysis verification of results.
As I reflect on the past 365 days that just came to a close, 2016 was the year I stopped seeking external validation and began learning to harness the only validation we ever need, that which comes from within, as there is nothing more powerful than our own sense of self worth.
Recent advancements in the utilization of residual dipolar couplings (RDCs) as a means of structure validation and elucidation have demonstrated the need for, not only a more user friendly, but also a more powerful RDC analysis tool.
Unions were more powerful.
