It is possible that overexpression of Tnfsf14 has a more potent effect in tissues facing a greater challenge to survival.
This is not surprising since higher exposure may result in greater tissue damage, and more potent and longer immunosuppression.
These studies highlight how even a single cell surface marker may be used in order to purify a more potent progenitor cell population for bone tissue engineering.
Overall comparison of the curves indicated that etomidate and propofol had a similar effect on KCl-precontracted aorta, but that etomidate was more potent than propofol in PHE-precontracted tissues.
Encapsulating therapeutic molecules in a tissue engineering scaffold allows local delivery of these molecules to regenerating tissues, possibly leading to a more potent effect and eliminating the side effects associated with systemic delivery.
DHEAS are androgen precursors secreted primarily by the adrenal cortex, which in peripheral tissues are converted to more potent androgens such as testosterone and oestrogens.
However, we did not observe significant differences in the efficacy of caffeine and a more potent drug, i.e., ZM241385, in the tissue model for PD.
By comparing the effects of similarly expressed wild-type and phosphomimic ARR1, we show that ARR1D94E is much more potent at promoting this type of cytokinin-independent tissue culture response.
DHT was effective at increasing both seminal vesicle and ventral prostate weights to the same extent, with or without T supplementation, which confirms many earlier studies that DHT is more potent than T in maintaining peripheral androgen-responsive tissues.
Furthermore, it has been demonstrated that GnRH-II has more potent effects than GnRH-I in extra-pituitary tissues, such as endometrial tumors, suggesting that GnRH-II could be considered as a possible therapeutic target for endometrial cancers [ 22].
