Sentence examples for more potent killing from inspiring English sources

These findings support and extend our and others' previous studies that phosphorylation of Bax at S184 can inactivate the proapoptotic function of Bax and that dephosphorylation of Bax at this site renders Bax more potent killing capacity [25] [27].

These results indicate that multi-epitope vaccines generated from human heparanase are capable of eliciting much more potent killing of tumor cells than their corresponding single peptides in vitro and ex vivo (Fig. 3).

In the search for MDR-overcoming drugs, we found that tanshinone-1 exerted more potent killing effects on MDR tumor cells than tanshinone-2A with resistance factor (RF) 0.9 versus 3.6 (unpublished data).

Here we show that combined treatment of emodin and cDDP induced a higher level of oxidative stress which was related to a more potent killing of cDDP-resistant ovarian cancer cells both in vitro and in vivo and stronger suppression of MRP1 expression.

These results clearly indicate that the CTL specifically targeted heparanase peptides that were presented in the context of HLA-A2 and the multi-epitope vaccines of human heparanase could elicit much more potent killing effects compared with their corresponding single peptides.

Although there was better killing activity of F6 against the mentioned strain starting from the beginning of the assay, the rate of killing was slower than F13 and F20 which showed more potent killing effect by time causing about 7.7 and 6.2 CFU/mL log microbial reduction after 24 hours, respectively, compared to 5.3 CFU/mL log reduction obtained by F6 after the same time.

Intriguingly, R9-rGel without the CPE targeting moiety displayed even more potent cell killing with an IC50 of 38 nM.

A recombinant immunoproapoptotic protein containing this sequence was previously shown to result in more potent cell killing activity than those with other furin-sensitive sequences [ 17].

This research shows for the first time that targeting of EGFR and IL-4R simultaneously with a BLT is a promising therapeutic option in the treatment of MM. Figure 1A reveals that targeting both receptors simultaneously with EGF4KDEL leads to more potent cell killing than targeting either receptor alone.

Dr. Mohr and a doctoral student, Matt Mulvey, then engineered a way for their virus to evade the immune system, making it an even more potent cancer-killing agent.

Cross-linkage of the ligand has a more potent cell-killing effect and more closely resembles the membrane-bound form of the ligand found in vivo [18].