Sentence examples for more potent based from inspiring English sources

While γ-cyhalothrin was 2-fold more potent based on administered dose, the differences based on internal concentrations were less, with γ-cyhalothrin being 1.3- to 1.6-fold more potent than λ-cyhalothrin.

The phytochemicals modify gA channel activity at low micromolar aqueous concentrations (the membrane concentration will be three-to-four orders of magnitude higher than the aqueous concentrations), with curcumin and EGCG being somewhat more potent (based on the aqueous concentrations) than the other compounds tested.

While some progress has been made toward developing more potent compounds based on the SAS scaffold (Shukla et al., 2011), the identification of system xc− inhibitors based on alternative scaffolds remains a pressing need and would be useful to test the hypothesis that system xc− inhibition is therapeutically beneficial in glioma and other contexts.

The results discussed herein could be useful in understanding the nature of interactions of these newly identified ligands as FSH receptor antagonists and in designing more potent ligands based on this novel 6-amino-4-phenyltetrahydroquinoline scaffold.

We aimed to design and synthesize a more potent hURAT1 based on the structure of Lesinurad (LU), which was reported to lower uric acid levels with IC50 value of hURAT1 (about 60 μM).

In addition, identifying individual miRNAs that regulate multiple cancer cell phenotypes such as anoikis resistance and metastasis will allow the development of a more potent miRNA based drug.

This will lead to the development of more potent statins based on better profiles of bioavailability, which will help open new promising therapies for looming and imminent outbreaks of influenza.

Nevertheless, because catalysts 1 were found to be more potent than those based on alternative chiral skeletons, further testing and optimization was conducted by using this chiral backbone.

Results of the current study provide an impetus to further evaluate the potency of these inhibitors against pathogenic P. aeruginosa strains in vivo and to design more potent antibacterial agents based on these AVS inhibitors.

The purpose of the study was to validate the experimental results obtained with Darunavir derivatives and to predict the compound that may developed into a more potent HIV inhibitor based on outcomes extracted from the current study.

The present study also provide important clues for drug design of more potent urease inhibitor based on the biscoumarin functionality.