Sentence examples for more physiological situation from inspiring English sources

In a second experiment, we examined the mitochondria in a more physiological situation by incubating permeabilized muscle fibers from the rat muscle with plasma from septic ICU patient or healthy controls.

Instead, cells gradually deplete glucose from the culture medium at a starting concentration of 5 mM glucose, mimicking a more physiological situation of hypoglycemia.

We performed further parallel studies in each experiment using doses resembling a more physiological situation for both UVA (6 J cm−2) and UVB (60 mJ cm−2) and detected similar trends (Figs S1 S3; see Supporting Information).

We observe that ROS levels go up in NCD4 cells as time of peripheral residence increases, whether in the severe situation of parking in MHCII-deficient mice, or in the more physiological situation of parking in WT lymphoreplete mice.

Parallel studies using doses resembling a more physiological situation showed similar results after both UVA (6 J cm−2) and UVB (60 mJ cm−2) exposure (Fig. S1; see Supporting Information).

Simulating more physiological situations in which all four substrates could be utilized, we determined an oleate and glucose percentage of 21%and79%9%, respectively, most optimal (C i + = 0.7334; see Table 3).

We speculate that the participants within the AD group have more consistent physiological situations and thus ROS production would be more closely associated with oxygen consumption, however, more work needs to be done to assess the impact of tissue and physiological conditions on mitochondrial ROS production.

In contrast, in the presence of ADP and MgCl2, mimicking more closely the physiological situation, STAT3-KO mitochondria tolerated less calcium until MPTP opening occurred (Fig.  6b).

We believe that osteoclasts cultured on bone slices should reflect the real physiological situation more closely, but the different results might be due to the interactions between the osteoclasts and the micro-environment on bone slices.

Importantly, our RNAi-based approaches represent more or less the physiological situation after contact with or ingestion of plant foods (i.e. challenge with an allergen mixture), in contrast to previous studies that reported histamine release assays conducted with only a single native, glycosylated allergen versus the recombinant, non-glycosylated allergen form [7], [14] [16].

In these cells, lower levels of protein accumulation might be more representative of the physiological situation.