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To learn whether a more physiological mode of Notch activation can induce HIF2α expression, we cultured MDA-MB-231 cells on immobilized Jagged1 or Dll4 ligands in normoxia.
Whether or not this points to CSII as a more physiological mode of insulin therapy compared to MDI remains to be seen.
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However this dual mode of action of PIs may be integrated in a more physiological way by using new multiscale viral kinetic models that explicitly integrate the effect of PIs on the intra-cellular viral dynamics [ 9].
The data presented here suggest that different miR-200 family members do not inhibit migration but have distinct effects on the mode of tumour cell migration when studied by invasion into a 3D collagen-I matrix, a more physiological model of the interstitial matrix.
However, there is a much more clear and compelling comparison to a fourth thalamocortical physiological mode described since the 1940s (in addition to the three already noted by the reviewer) – the production of high voltage spike-wave activity associated with behavioral arrest.
At higher more physiological salt concentrations, SSB binds in the fully wrapped binding mode and exhibits 'limited' cooperativity, where SSB forms dimers of tetramers (i.e. octamers) along the ssDNA (Bujalowski and Lohman, 1987; Lohman and Ferrari, 1994).
It's more physiological than that".
Depending on their specific operational characteristics, these modes can assist spontaneous breathing efforts synchronically in time and magnitude, adapt to changing patient demands, implement automated weaning protocols, and introduce a more physiological variability in the breathing pattern.
Divorce puts women under significantly more physiological strain than men, research reveals.
ETV is a more physiological treatment than VPS.
MR: I think the disappointment for many was that it was more physiological than action packed.
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