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To realise the full potential of analysing perturbation phenotypes by single-cell gene expression profiling, more physiological means to tune gene expression levels are therefore required.
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Indeed, we demonstrate here that the stimulation of the monocytes with PMA (which although non-physiological is usually applied to differentiate monocytes over a short time to a macrophage-like phenotype) and the more physiological induction of monocyte differentiation by means of M-CSF cause the translocation of HIF-1α into the nucleus of long-living tissue macrophages.
This means that, per minute, you get more physiological bang from intervals, an important consideration if your exercise time is limited.
It's more physiological than that".
Divorce puts women under significantly more physiological strain than men, research reveals.
ETV is a more physiological treatment than VPS.
MR: I think the disappointment for many was that it was more physiological than action packed.
But what happens under more physiological conditions?
"Positive health" can be achieved therefore using physiological means like an adequate physical activity and exercise, which has been however known and experienced long time ago, however, more and more difficult under present conditions of life.
One limitation of our study is that we have not used in vivo blastocysts which might have provided more biological means and as the physiological standard against in vitro culture conditions.
More ticks means more Lyme disease.
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CEO of Professional Science Editing for Scientists @ prosciediting.com