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We acknowledge the limitations of this work and agree that there would be advantages to taking pulmonary arterial samples to give more physiological data.
We found two more relevant and more physiological data sets, i.e. ex vivo virus infection-induced profiles in PBMC from infected children.
For this reason, more physiological data on these issues are needed before the promising technique of miniaturized veno-venous ECCO2R can be tested in a broader clinical setting.
Further reduction in the numbers of such animal tests may be achieved if more physiological data can be obtained from assays in simpler organisms such as zebrafish.
On the other hand, a multicompartment model, e.g., the physiologically based toxicokinetic (PBTK) model developed for fish by Nichols and co-workers, may be viewed as more complex than one-compartment models because it requires more physiological data and simulates multiple compartments.
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Overall, the kinematics of the ACL-deficient knees seemed to be more physiological than data reported for TKA, but not as close to healthy knees as ACL-reconstructed UKA knees.
Additionally, these 3D models may provide more meaningful physiological data in drug discovery and toxicology assays.
When a more substantial library of PN physiological data becomes available, the same technique can be used to generate a more exact functional prediction of PN input to the LH and MB.
First, detection imposed higher subjective workload and distress than other tasks, but physiological data suggested more complex differences between tasks.
The gene lists were analyzed against the gene list of the human genome since the annotation of the human genome, especially with physiological data, is more advanced than the chicken genome.
Indeed, this idea is also borne out by published data from more physiological circumstances [ 40- 42].
More suggestions(11)
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