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For these studies the cells were plated on a thick deformable layer of collagen-I because this substrate mimics aspects of a true 3D matrix and represents a more physiologic environment for studies of melanoma cell migration [1].
HA is a natural substrate for osteoblasts that could contribute to create a more physiologic environment.
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Unlike traditional in vitro biochemical analyses, cell-based assays more closely mimic the actual in vivo physiologic environment, addressing simultaneously biological activity and toxicity issues.
A promising new strategy to converge these approaches is the use of tissue engineering to create more physiologic in vitro models, which are controlled and yet also mimic the complex in vivo environment.
Fibroblast cells are plated on top of the fibrin gel to further mimic a physiologic environment.
More physiologic type of fixation and a good ability to maintain reduction in syndesmosis.
Slow maxillary expansion produces more physiologic response at the mid-palatal suture area.
The effect of more physiologic flow dynamics on coronary artery flow has not been investigated yet.
Hence, the soft stabilization system was designed with the aim of more physiologic stabilization.
Suckling done by the child during breastfeeding is more physiologic and promotes a better oro-facial development.
Portal venous drainage of small bowel grafts is theoretically more physiologic than systemic drainage, but is technically more demanding.
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CEO of Professional Science Editing for Scientists @ prosciediting.com