People with cognitive impairment are more likely to be physically frail [ 9], are more likely to suffer orthostatic hypotension [ 10] and with age-related and arteriosclerotic changes to cerebral blood flow auto-regulation are more vulnerable to resulting cerebral hypoperfusion [ 11].
However, people with dementia were significantly under-represented in these studies and as a population are more likely to be physically frail, to suffer orthostatic hypotension and to experience adverse effects from polypharmacy at a lower drug count.
The duration of the interventions ranged from 10 weeks 28, 29 to 18 months, 32, 33 and the majority included older adults who tended to be more vulnerable as they were physically frail, 27– 29, 34, 35 nutritionally "at risk" 30 and/or had other comorbidities; 31 one study evaluated the effects of a nutritional supplement provided as part of a government nutrition program.
Our study population was more highly educated and more physically active than the general elderly population in Hong Kong, so our findings cannot be generalized to those who are institutionalized, the frail elderly, or those with a lower education level.
Participants: Eighty-four physically frail older adults (mean age, 83 ± 4yrs).
A prehabilitation program for physically frail community-living older persons.
She's so mentally and physically frail now".
A program to prevent functional decline in physically frail, elderly persons who live at home.
McGuinness resigned from office in January appearing physically frail, which prompted fears he was gravely ill.
Physically frail but cleareyed, and in love with the sea and all it signifies, she can also be seen as an alter ego for O'Neill, quite possibly more than any female character in his major works.
