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In the longer term, quinpirole-treated rats made significantly more perseverative EOLPs per minute of light illumination than vehicle-treated counterparts.
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The instrument has been shown to be sensitive to frontal lobe damage; people with frontal lobe damage tend to make more perseverative errors.
This task demands cognitive flexibility and strategies to deal with the environmental contingence (Nyhus and Barceló 2009), and the extra-frontal lesion group needed more cards to complete the task, as well as making many more perseverative errors.
While lowering the Hamming distance in the Hamming block gave rise to progressively more perseverative responses, changing the threshold vector of the Hopfield network resulted in more set maintenance failures.
A Group (lower-, higher-SPS) by Condition (WCST, EFCST) by Sorting Rule (color, form, number) interaction was expected in which the higher-SPS EFCST group would have worse overall performance and make more perseverative errors than the other groups.
After controlling for these compared to controls marijuana-using participants made significantly more perseverative and total errors on the WCST and showed significantly impaired (e.g., less adaptive) response allocation to the changing reinforcement contingencies on the concurrent-reinforcement task.
On the other hand, AN patients committed more perseverative errors demonstrating more cognitive rigidity.
Another reason is that the SHR has more perseverative response in shifting.
This indicates that the SHR has more perseverative responses and is more impaired in maintaining a new rule.
The prediction that more stereotypic individuals would show evidence of more perseverative cognition was a major motivator for this project.
Second, in the current study we found no evidence that more stereotypic starlings had more perseverative cognition.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com