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More patients reported no difficulty in micturition and in defecation and more patients received analgesics compared to before protocol implementation.
Similarly, significantly more patients reported total migraine freedom at 2 h after rizatriptan (51%%) than after placebo (8 %) (therapeutic gain 43 % [26 %; 61 %]; P < 0.001).
Posthoc analysis indicated that more patients reported no migraine days with fremanezumab monthly dosing (79.4%; p=0.0002) and fremanezumab quarterly dosing (79.2%; p=0.0004) versus placebo (66.6%) by the next day following first injection.
Posthoc analysis indicated that more patients reported no headache of at least moderate severity with fremanezumab (69%; p=0.0036) versus placebo (61%) by the next day following first injection.
More patients reported a metallic taste in their mouth with the metformin than with the placebo treatment (metformin: n = 7; placebo: n = 1; p = 0.029).
More patients reported a better sleep perception after sleeping with earplugs in the ICU.
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After aggregating available data by generic ingredient, 220 prescription treatments met the inclusion criteria of 50 or more patients reporting side effect information (Fig. 1).
Prior to coding, a pre-specified threshold of 25% (i.e. three or more patients reporting a consistent problem) of interviews had been set as a guideline for determining whether the reported problem warranted a change, although this was a guideline rather than a rule.
The self-evaluated health transition item at week 48 showed slightly more patients reporting improvement than patients reporting deterioration, in contrast to the baseline status.
Lubiprostone exhibited a rapid onset of effect, with significantly more patients reporting an SBM as early as 4 h after the initial dose of lubiprostone compared with placebo.
With 40% or more patients reporting high satisfaction on most question items, the potential strength of trends with independent measure of health status are in turn reduced.
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more patients died
more hospitals reported
more places reported
more men reported
more females reported
more patients diagnosed
more people reported
more companies reported
more pollsters reported
more families reported
more manufacturers reported
more deaths reported
more households reported
more males reported
more upgraders reported
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com