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The Western Reserve strain of VACV (VACV-WR) is relatively more pathogenic for mice than other strains of VACV, due to its previous adaptation to grow in mouse brain [3].
We cannot yet say whether BASE is more pathogenic for primates (including humans) than cBSE, nor can we predict whether its molecular biological features represent a clue to one cause of apparently sporadic human CJD.
These findings illustrate that BTV-8 was more pathogenic for sheep than for cattle.
B. melitensis and B. suis are considered more pathogenic for humans than B. abortus (7).
This argument is supported by experimental evidence that over time HPAIV (H5N1) has become more pathogenic for domestic ducks.
Polymicrobial infections are known to be more pathogenic for experimental animals than are those involving single organisms [ 35].
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As a result, high temperature environments could indirectly select for more pathogenic bacterial pathogens at both phenotypic and genotypic level.
Certain AβDPs also have the potential to impact the relative abundance of more pathogenic forms of Aβ (for example, Aβ42) relative to more inert forms (for example, Aβ40).
Free-living water and soil-borne bacteria with no specific pathogenicity characteristics, but which are thought to provide reservoirs for more pathogenic bacteria, have now also been found to harbour GEIs.
S. epidermidis and S. sanguinis are not usually associated with active peri-implantitis, but they are amongst the main early colonizers of oral tissues and artificial biomaterials, paving the way for more pathogenic species [56 58].
If BASE is more pathogenic than classical BSE for primates, it could indicate a more readily transmissible infection from cattle to humans than previously suspected.
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CEO of Professional Science Editing for Scientists @ prosciediting.com