Sentence examples for more open conformation from inspiring English sources

Structural modeling in the absence of calcium suggests that mini-calpain-5 adopts a more open conformation when compared to previously determined structures of other calpain cores.

Polymerization also produced deuteration increases for peptide fragments containing the ATP phosphate-binding loops, suggesting G-actin transitions to a more "open" conformation upon polymerization.

Compared with differentiated somatic cells, ESCs have unique features: they have a more "open" conformation of chromatin structure, including the telomeric region.

In the absence of cAMP, this region moves slightly away from the PBC resulting in a more open conformation.

These data support a model in which SM proteins hold their cognate syntaxins in a closed conformation and thus regulate SNARE complex assembly, perhaps by facilitating the switch of syntaxins from their closed to a more open conformation [7].

Since a conformational change from a closed to a more open structure is likely the rate-determining step in the IDE reaction, the subunit induced conformational change likely shifts the structure of the oligomeric enzyme to a more open conformation.

The trimer is flexible, fluctuating between closed and more open conformations and sometimes sampling the fully open, CD4-bound form.

The "closed," antibody-resistant Env trimer is driven to more open conformations by binding the host receptor, CD4.

The acceptor site explores more open conformations, similar to the case in which the 4-methylumbelliferone is absent.

5) The authors propose that the reduced τc values for the charge reversal mutation indicates a shift to more open conformations.

Two recently published crystal structures of human IKK2 reveal that the dimer can adopt significantly more open conformations in which the KD ULD swing away from one another, suggesting that dimerization is mediated entirely through portions of the SDD that are distal to the KD.