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Patients with ESBL-PE related sepsis had more often septic shock and bacteraemia at admission.
Patients receiving SAT for SIC were more severely ill than those having SAT for PIC: they had higher severity scores and more often septic shock.
ESBL-PE pneumonia was associated with higher SAPS II and more often shock at admission, as well as a higher SOFA score and more often septic shock at pneumonia onset.
Patients with ESBL-PE pneumonia had a higher SOFA score, more often septic shock at pneumonia onset and higher in-ICU mortality (58 vs. 38%; p = 0.034) (Table 2).
Serotype 3 caused significantly more often septic shock (OR 6.33 [CI 1.59-25.29]) compared to serotype 14.
In analogy with Garcia-Vidal et al.[ 12], we found that serotype 3 gave significantly more often septic shock and higher mortality compared to serotype 14.
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Interestingly, we found that the frequency of septic shock differed between serogroups and that serotype 3 significantly more often caused septic shock as compared to serotype 14.
If compared to non -CRKP pts, CRKP pts were more often in septic shock (75%% vs 34%%, p = 0.031) and more frequently underwent CRRT (75%% vs 36%% p = 0.0404).
S. pneumoniae serotype 3 more often caused septic shock compared to serotype 14.
Patients infected with S. pneumoniae serotype 3 significantly more often suffered from septic shock compared to patients with serotype 14.
Patients with progression of AKI more often suffered from septic shock (134/153, 87.6%) compared to those without progression (185/270, 68.5%), P <0.001.
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