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After exposure to glutamate for 5 h or more, neurons expressed less KCa2.2 channels and around this time point NS309 lost the neuroprotective potential.
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More neurons expressing K44A-dyn failed to migrate at all, but those that did move had slower rates than cells expressing WT-dyn (Figure 2D).
We reasoned that a shift toward larger somal sizes would indicate that more pyramidal neurons were expressing MR-GEF while a shift toward smaller somal sizes would indicate that more GABAergic neurons expressed this gene.
We found that more adult-born neurons expressed Arc in animals allowed to explore, than in cage control animals, indicating that adult-born neurons have a specific Arc-expression response to spatial exploration [2].
Results: Presumed inhibitory neurons expressed significantly more GAD65, GAD67, vGAT, GABAA-receptor α3, and N-methyl-D-aspartate (NMDA -receptor IIB mRNMDA -receptored excIIBtory neurons expressed mRNA GandA-recepresumed and NMDA-rexcitatorymRneurons
This resulted in a significant difference; NPY neurons expressed significantly more FOS-IR than α-MSH neurons (t(3) = 11.8, p ≤ 0.001).
A proportion of neurons expressed the synaptic marker PSD95 and GABA A-receptor, indicating a more mature neuronal phenotype.
A consequence of these life-extending mutations is often extensive metabolic reprogramming (Artal-Sanz & Tavernarakis, 2008), and our work suggests that certain metabolic outcomes are more favorable to neurons expressing toxic proteins than others.
Lennerz et al. found that 63% of the neurons expressed CLR and 35% of the neurons expressed RAMP1 [20].
Both glia cells and neurons expressed kif21b.
In normal TG neuron culture, 14% of neurons exclusively expressed the P2X3 subunit, 17% of neurons exclusively expressed P2X2, and 19% neurons expressed both subunits.
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