Sentence examples for more negative membrane from inspiring English sources

When tested on the insect voltage-gated Na+ channel (para) of the fruit fly, this toxin was able to induce a clear shift in activation (V1/2), resulting in the opening of the channel at more negative membrane potentials.

Fluorescence readings of differentiating cells decreased in intensity as a function of differentiation time, which corresponds to more negative membrane potential, or hyperpolarization.

Thus, neurons related to acid-exposed masseter muscles functioned at more negative membrane potentials, but yet were more excitable, and more likely to fire spontaneously than control cells.

Recent experimental studies across a variety of models have suggested that oxaliplatin modulates axonal voltage-gated Na+ channels, specifically by slowing Na+ channel inactivation kinetics [7] [9], shifting the voltage dependence of inactivation to more negative membrane potentials [10], or reducing Na+ current [10], [11].

In particular, Pacific ciguatoxin-1B (P-CTX-1B previously called CTX and CTX-1b) has been shown to enhance voltage-sensitive Na+ channels activity by shifting their activation to more negative membrane potentials, and by inhibiting in part their inactivation [8].

These results may be consistent with the observations that the antiepileptics shift the steady-state inactivation of Na+-channel currents to a more negative membrane potential [ 21– 23].

High membrane roughness and zeta potential (i.e. more negative membranes) along with high monovalent cation concentrations in the feed water were observed to contribute to biofouling control.

Consistent with this, loss-of-function CaSR−/− mutant neurons have a more negative resting membrane potential [28] which could reduce the likelihood of seizures.

This developmental transition is characterized by a switch from slow skeletal to cardiac TnI, an increase in binucleation, cardiac calsequestrin and hypophosphorylated Rb, a decrease in E2F3, B-Myb and atrial natriuretic factor, and the establishment of a more negative resting membrane potential.

EJPs evoked at 15 Hz in the absence of Dube3a (Dube3a 15b homozygous mutant larvae) decayed more rapidly over the course of 30 stimulations compared to w controls, and Dube3a 15b larval muscles had significantly more negative resting membrane potentials (RMP).

Expressing R196Q and F304Y mSlo3 resulted in a significantly more negative oocyte resting membrane potential compared with control oocytes or those expressing WT mSlo3.