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Exact(5)
7% (6/86) of tumours exhibited considerable inhibition, but most showed a more modest response resulting in a low TGI.
The trends shown in Figure 2 indicate that the inflammasome may be significantly induced during more lethal infections and might show a more modest response in macaques.
7% (6/86) of tumours exhibited considerable inhibition (>50% inhibition at 100% TDC), but most showed a more modest response resulting in a low maximum percentage inhibition.
However, a second phase-III trial of the regimen reported a more modest response rate of 43% from the combination (33.6% with FOLFIRI), possibly due to the lower doses of all three agents used.
As judged from the more modest response to VEGFC, compared with VEGFA, in angiogenic sprouting in the 3D EBs, VEGFR3 homodimers on the other hand may not contribute to sprouting.
Similar(55)
Moreover, the mutations do not identify the large number of patients that achieve more modest responses.
Similarly to the observation obtained by comparing each time-point to day 0, the peak-intervening time-points are characterized by a more modest transcription response and may reflect resumptions of the local homeostasis resulting from the transient adaptation to excess dietary fat.
Specifically, the adult offspring of high-compared to low-LG-ABN mothers exhibited decreased levels of hypothalamic CRF mRNA and increased hippocampal GR mRNA expression, which was accompanied by an increased sensitivity to glucocorticoid feedback and more modest HPA responses to acute stress (Liu et al., 1997).
At the highest tested concentration of 50 mg/ml, secretion was enhanced approximately ninefold (Fig. 1a), while the lower peptone concentration of 5 mg/ml peptone triggered a more modest approximately threefold response.
In turn, VILI induces a more modest acute inflammatory response with mild lung neutrophil accumulation and distinct mechanisms leading to inflammation and barrier dysfunction involving a different set of signaling molecules [ 23, 45- 47] and transcription factors [ 48].
While these differences were statistically significant at telomeres (P=0.03), whole genome analysis revealed a more modest impact in response to oncogene activation (Supplementary Figure S7B), despite equal DNA labelling rates (Supplementary Figure S7C).
Related(20)
more restrained response
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