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Of all women who wanted to get pregnant, 3946 (25.1%) had one or more miscarriages, with an average of 1.4 (±0.9) miscarriages and a maximum of 10 miscarriages.
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To compare subsequent pregnancy outcomes after two or more miscarriages in patients with and without congenital uterine anomalies.
There was a dose response relationship, as evidenced by stronger associations for women with three or more miscarriages than for women with one or two miscarriages, for each outcome, and by the significant per-unit increase.
The resulting sample included 449 women with a history of one or more miscarriages and 2349 women with no history of miscarriage.
There was evidence of an association of high titres of IgG ACL and IgM ACL among women reporting three or more miscarriages, and among women with three consecutive miscarriages, but this was experienced by just five of the 97 women with SLE who reported ever being pregnant.
After excluding incomplete data sets, the final analysis was based on 560 fertile women with a history of 3 or more miscarriages, which included 132 patients with 5 or more miscarriages.
The prevalence of congenital uterine anomalies in women with two or more miscarriages appears to be similar to those with three or more miscarriages, regardless of the diagnostic test used.
Furthermore, 3946 (25.1%) women in this group had one or more miscarriage(s), with an average of 1.4 (±0.9) miscarriages and a maximum of 10 miscarriages.
We will end up with far more miscarriages of justice".
According to the NHS, it occurs in one in six known pregnancies, with many more miscarriages happening before a woman is even aware she has become pregnant.
Among women who reported three or more pregnancies, there was no apparent difference in risk of three or more miscarriages (any gestation) between women with SLE and without SLE (6/64 (9.4%) versus 9/128 (7.0%), respectively; P = 0.6).
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