In the other half of subjects (termed DAT-i inflexible, with a "stuck" profile), a more marked impairment emerged: a net preference for LL seemed to be expressed, which was likely the result of a rigid pattern of choice.
Note that mice with a "flat" or a "slow" profile do share a common feature, that is, they display as a whole a more marked attraction to LL, compared to mice with a "steep" or a "stuck" profile.
A poorer response to purine nucleoside analogues (PNAs) is observed in patients with more marked leukocytosis, bulky splenomegaly, an unmutated immunoglobulin variable heavy chain (IgVH) gene profile, use of VH4 34 or with TP53 mutations.
However, when looking at the profile for the oldest patients at Skien there is an even more marked drop in survival of about 8 12 days after start of admission than seen for 2008 2009.
Conversely, within the semantic dementia syndromic group, the Pick's and the TDP-C pathological groups exhibited very similar profiles of atrophy within the temporal lobe but the Pick's disease subgroup was associated with more marked asymmetry of temporal lobe involvement and additionally associated with more marked, asymmetric parietal lobe atrophy (Supplementary Table 3).
The contrast with the UK could not be more marked.
The contrast with Michael Phelps could hardly be more marked.
Nowhere was this more marked than in writing.
A more subtle, but more marked, effect of within-family sex has emerged in Iceland.
The sour taste has become more marked with the fall of communism 15 years ago.
