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We hypothesize that CNTNAP2 variants which usually yield only a small boost or lag in language acquisition will have more marked consequences when they occur in concert with other genetic or environmental risk factors.
The more marked consequences of Aβ42arc expression are thought to be due to the increased aggregation propensity of this peptide and to its oligomer-rich aggregation mechanism (Nilsberth et al., 2001; Whalen et al., 2005; Luheshi et al., 2007).
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Among the labor movement, a more marked consequence of Autumn 1917 was the rise of the Workers Guardss.
A more subtle, but more marked, effect of within-family sex has emerged in Iceland.
The association of biofeedback and pharmacological therapy induces a more marked effect [409].
Potentially slight changes in expression of p53-related genes were obscured by more marked transcriptional consequences of Rpl11 deficiency in zebrafish embryos.
This effect was more marked for GO than for AVE9633.
The effect appears more marked in those with active disease.
The trend to more marked swelling at the injection site was without consequence and did not lead to any drop-outs.
These associations are certainly biologically plausible as higher PSTRs are considered a functional consequence of morphological alterations at the level of the peritoneal membrane (i.e. peritoneal membrane injury), which are likely to be a result of or lead to more marked intraperitoneal inflammation.
Based on our genotype phenotype observations above, we hypothesized that the functional consequences of the co-occurrence of PTEN and SDHx alterations would be more marked, beyond those of SDHx alteration alone.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com