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The main difference is that the new approach can detect more main-effect and epistatic QTLs than the GWAS.

80% of service clients received one-to-one counselling but open group forms of behavioural therapy were more successful (main effect OR 1.26 (1.12 to 1.41)) except amongst some of the most disadvantaged clients (long-term unemployed and prisoners).

More critically, the main effect of synapomorphy condition was significant, F 1, 109) = 10.33, p < 0.01.

More importantly, the main effect of arithmetic complexity was observed in the left and right angular gyrus, while the main effect of rate of stimulus presentation was observed in the left insular/orbitofrontal cortex.

More specifically, the main effect of participant ethnicity may be due to generally faster processing speed of Japanese participants.

As expected, longer SOAs were associated with significantly more "long" responses (main effect of SOA: (F1,22 = 460.3, P < 0.0001, η2 = 0.95).

A mixed design ANOVA (2 Groups × 2 Road Types) showed significant group differences in the proportion of distance travelled over the speed limit with the ADHD group speeding more than the control group (main effect Group) and more speeding on the motorway than in the urban area (main effect Road Type), but no Group by Road Type interaction (see Table  2).

Both groups made more working memory errors and again the NR1 ΔDG mice made more errors than controls (main effect of group for square root transformed data, F1,22 = 10.0, P < 0.005; main effect of block, F5,110 = 10.5, P < 0.0001; groups by blocks interaction, F < 1).

Pfizer was looking for a new heart treatment and realized that a drug candidate's unexpected side effect was more useful than its main effect.

But it is more likely that the main effect will be to deepen cynicism and further entrench anti-Israel sentiment in the West Bank and Gaza.

McKay method needs about 360 samples to evaluate the main effect, more than 1000 samples to assess the two-way interaction effect.

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