More large scale studies on young NSCLC patients are warranted.
However, in the future, the clinical implication of quantitative RT PCR findings will be derived from the clinical follow-up of these patients or a more large-scale study.
Despite large differences among these studies in both design and results, individual results are promising and provide ground for more large-scale studies with standardized serial assessment of patient samples in the future.
We conclude from the few well-designed and replicated studies that there is a bias towards modelling approaches and small-scale fragmentation experiments, so more large-scale studies on a community level are needed to quantify the functional roles of insects and their dependence on fragmented calcareous grasslands in the landscape mosaic.
More large-scale studies are needed for complete understanding of arsenic metabolism.
Although the field needs more large-scale studies to guide the protocol selection process, inattention to this aspect of care may be costly.
Of late, more large-scale studies have started to emerge in both mouse and human systems (Villanueva et al., 2011; Söhle et al., 2012).
More large-scale studies in different ethnic background population are warrant to validate the potential role of ESR2 rs1256049 in susceptibility to CRC.
In the future, more large-scale studies should be carried out to confirm or refute the relationship between IL-18 polymorphisms and the risk of allergic disease.
Therefore, the conclusion should be interpreted with caution and more large-scale studies are warranted to confirm the results in the future.
Two systematic reviews [ 138, 153], and two large critical reviews [ 77, 125] conclude that glutamine and growth hormone at present time can not be recommended in short bowel syndrome; more large-scale studies, or multicentered clinical trials are required.
