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Hence a definite conclusion cannot be made and more large-scale population studies will be much required to clarify this finding.
Second, although the results showed that the rs7044343 CC genotype of IL33 is associated with lower serum IL-33 levels, more large-scale population study and functional experiments are needed to elucidate the association.
Therefore, we need more large-scale population-based studies to identify the real risk factors.
Along with improving modeling capabilities, it will be necessary to improve variant callers and to spend more time and effort on large scale population genomic assemblies.
More large scale studies on young NSCLC patients are warranted.
In large scale population-based whole-exome sequencing (WES) studies, there are some samples occasionally sequenced two or more times due to a variety of reasons.
Large scale population-based studies have not yet been conducted.
In a vicious circle of technology improvement, more large-scale sequencing studies on individual populations are needed to design more robust bead arrays, however these large sequencing projects can utilize the current bead arrays to improve genotype calling in low coverage regions.
More large-scale studies in different ethnic background population are warrant to validate the potential role of ESR2 rs1256049 in susceptibility to CRC.
Dynko predicted there would be no more large-scale protests.
The scale of the cash injection and support required this time has necessitated much more large-scale action.
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