Simplicity and quick convergence is the advantage of the method in comparison with other much more laborious numerical methods which require extensive computer facilities.
Although the heterologous expression of these bacterial laccases in E. coli made it possible to characterize the recombinant laccases and perform detailed structural analysis, the yields were often low or the proteins formed inclusion bodies, which made purification more laborious.
Fosmid paired-end sequencing, which is a more laborious technique, has been used to detect SVs larger than 8 kb [ 17, 18].
Mars-Jones, offering another character this year, said Squire's winning bid was "about as much as two months' subscription to a gym... which is a rather more laborious way of aspiring to eternal life".
Moreover, the benefits deriving from a higher consolidant absorption, as achieved by poultice and immersion applications (which are however much more laborious on site) are not so great in terms of HAP distribution in the substrate and consolidating performances.
This approach has the potential to replace culture-based, single cell, and flow cytometry-based genomics methods, which are costlier and more laborious due to the requirement for cell manipulation.
This model allows for relatively rapid assessment of the tumor burden in bone and is not dependent solely upon radiographic imaging and histology, which are less sensitive and more laborious, respectively.
While camouflage art is a frequent feature in Merry's body of work -- she previously painted nude models into murals around San Francisco -- the skyline project, which she began in May, is more laborious since the backgrounds are constantly changing.
But it's these interactions here—even if you don't participate in them, which you don't that are loads more laborious and annoying than any version of saying "goodbye my friend and happy birthday" would've ever been.
This method, which does not involve re-embedding, is far more laborious than that adopted by the Fleissner group, but yields higher quality images limiting potential artifacts.
