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Significantly more isolates from HIV seropositive patients (50%) showed reduced susceptibility to penicillin compared with isolates from HIV seronegative patients (16%), and high level resistance (MIC 1.0 mg/l or higher) was found in 16% isolates from HIV positive patients compared with 6% isolates from HIV seronegative patients.
This finding motivates us to collect and genetically characterize many more isolates from this locality and nearby areas to assess whether this group is endemic.
Phylogenetic analyses of six concatenated whole genomes and the hemagglutinin (HA) gene of seven more isolates from May-September 2009 was performed with reference to 685 whole genomes of global isolates available as of November 24 , 2009
Alternatively, as this ST differs from ST667 by just one base substitution at a single MLST locus, it is possible that further sampling will lead to the recovery of more isolates from ST668.
However, this hypothesis would need to be confirmed by genotyping more isolates from both geographic regions.
A cluster was defined as two or more isolates from different patients with identical spoligotype patterns.
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