Sentence examples for more invasive behavior from inspiring English sources

It can also be involved in degradation of COL16A1, COL17A1, COL18A1, and COL21A1 and more invasive behavior of these cell lines.

DSP is a key component of the desmosomes that form intercellular junctions and loss of its expression is associated with more invasive behavior of cells [ 54].

Taken together, the mechanical effects of increased CXCR2 expression, such as increased cytoskeletal remodeling dynamics and force-generating capability, provide a plausible mechanism for the more invasive behavior seen in these tumor cells.

Furthermore, class A expressed transcripts that we previously observed to be expressed in melanoma with more invasive behavior such as WNT5A [ 8] or MAGEA genes [ 31, 32] while Class B was enriched with transcripts associated with better prognosis [ 8] and the expression of melanocytic lineage specific genes [ 43] denoting a higher status of differentiation.

Moreover, in cocultures with primary fibroblasts derived from colon cancer tissues, CD133+ cells exhibited significantly more invasive behaviors than CD133− cells (P<0.001), especially in cocultures with CD10+ fibroblasts (P<0.0001).

Numerous evidences supporting the more invasive biologic behavior of KCOT were related to the upregulative expression of MMPs [ 15, 16].

This raises the question of possible downstream effects of pathways that may contribute to a more invasive and motile behavior of tumor cells.

14 Furthermore, in nonresected primary tumor animal models, angiogenesis inhibitors targeting the VEGF pathway demonstrated antitumor effects but concomitantly elicited more invasive or metastatic behavior.

Id proteins, especially Id1, are associated with a more aggressive and invasive behavior, as well as with a less differentiated tumor phenotype, and in some kinds of tumors, as markers of cancer diagnosis and progression [ 28].

When they say it's only the shoulders, how do they know?" Dr. Anne H. Meltzer, a psychologist who specializes in child sexual abuse with offices in Manhattan and Westchester, said it was common for sexual predators to desensitize their victims by beginning with "more benign contact" and progressing to "more invasive kinds of touching behaviors".

Home cage observation poses minimal disturbance of the dam and her litter as compared to more invasive assessments of dams' emotional behavior.