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This loss of methylation as tumors progress to later grades may indicate changes in tumor heterogeneity resulting in refinement of the most beneficial effects of hypermethylation as proposed above, but could also represent a potential increase in normal contamination as the tumor becomes more invasive and thus the tumor sample more intermingled with normal.
In addition, throughout human islets β cells are more intermingled with the other islet cell types (mainly α and δ cells).
Similar(58)
Small black pigs root around them, and hidden in the pond, though the pasis deny it, there are barrels of fermenting mahua flowers.Shahabpur's smaller caste-groups are more intermingled, though discreetly separated by walkways and ditches.
In fact, an emerging view is that gene regulatory and coding sequences are more intermingled than once believed [ 80].
Belgian and Australian strains were more intermingled in lineage 2, while separate clusters of Belgian or Australian strains were more frequently observed in lineage 1, indicating more localized epidemics in each country (fig. 3 A).
In the publication map, these two clusters are more intermingled than the others, which is especially well visible when zooming in on the area of the two clusters (figure 1B).
Southwards, the tree layer becomes more open and intermingled with Acacia species (Burke 2002).
In the resting ECoG, a physiological theta rhythm more or less intermingled with alpha and delta activity was prevailing in all animals.
Intermingled with the smaller colonials are many substantial houses.
Concrete sensory experiences, like vision, intermingled with cognitive abstraction, and cognitive abstractions reshaped visual imagery.
I noticed an ornate glassed-in cabinet where Greek and Latin books intermingled with yellowing physics tomes.
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