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One provider reflected on where cost savings might accrue: ' If you take somebody with dementia, clearly they may well need more intensive acute services sooner than they would do, particularly because of their co-morbidities, more social care etc, so the actual saving isn't going to be in [our] services necessarily because we are only a small part of wider services for people with dementia.
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For example, the benefits of warfarin in atrial fibrillation, the benefits of aspirin and statins for primary prevention of coronary heart disease, and the benefits of more intensive therapies for acute coronary syndromes have all been shown to be dependent on baseline risk, which requires the simultaneous assessment of multiple clinical risk factors.
Despite treatment advances and more intensive clinical monitoring, rehospitalization due to acute decompensation of HF remains high, with pulmonary congestion being the most common precipitant for re-admission [ 2].
For patients diagnosed with persisting CAA after the acute phase, both guidelines advise a more intensive and prolonged follow-up with additional imaging modalities.
Despite that, the more intensive regimen has not been widely accepted due to long term adverse events, like acute myelogenous leukemia, myelodysplastic syndrome and lung cancer [ 40].
"It's much more intensive.
"The gunfire became more and more intensive.
It's quicker and more intensive".
"We then launched a more intensive investigation".
But it gets much more intensive.
For example, acute lymphoblastic leukemia (ALL) with t(1 19) responds poorly to conventional antimetabolite-based treatment but has cure rates approaching 80% when treated with more intensive therapies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com