In information theory, the entropy statistic is a standard scoring method that quantifies the information encoded in a given random variable, where higher entropy implies a more informative distribution.
Indeed, future improvement on this issue will allow us to use more informative prior distributions at the different nodes of BET_EF.
More informative prior distributions are available as part of the SIAR software.
In the meantime, the use of responder rates of patients experiencing a minimum change from baseline in SGRQ scores – or perhaps more informative, cumulative distribution plots – may be a useful assessment, as research suggests that it may be less dependent on the exact cutoff, i.e. the precise value of the MID [ 46].
The posterior distribution over rate constants V was much more informative than the posterior distribution over Michaelis Menten parameters K, consistent with the 'weak identifiability' of kinase inhibitors that we found in Section 3.1.
The improvement on resolution of ChIP-seq will make the distribution more informative, which can potentially boost the accuracy of the algorithm.
Small effect sizes like these are normal with clinical trials and it may be more informative to examine the distribution of responses between treatment groups [ 24].
When clinical trials show small mean effect sizes, rather than considering results in terms of an MID, it may be more informative to examine the distribution of responses between treatment groups to more fully characterize the treatment effect and examine the possibility that the mean improvement reflects very different responses in subsets of patients.
Also, rather than showing one example, it will be more informative to show the distribution of division planes relative to the wing disc epithelium from multiple examples, akin to the "pie chart" that is often used in studies of neuroblast asymmetric divisions (for example, see papers from Chris Doe's lab).
