Sentence examples for more hypoxic phenotype from inspiring English sources

Moreover, it is known that TNBC is associated with a more hypoxic phenotype possibly due to activation of the mTOR pathway and HIF-1α stabilisation [153].

Clinically, the fact that TNBC's are amenable to fluroeoxyglucose-positron emission tomography (FDG-PET) scanning as a result of the "Warburg effect" [154] also highlights their more hypoxic phenotype (Table 3).

Since the hypoxic phenotype is more migratory than the normoxic one (Berens and Giese 1999; Giese et al. 2003; Bristow and Hill 2008; Gorin et al. 2004), hypoxic cell diffusion coefficient D h is larger than the normoxic one D n.

Moreover, the administration of antiangiogenic agents, particularly antibodies against VEGF, leads to a more hypoxic tumor microenvironment [ 31], which enhances tumor cell invasion and metastasis by inducing the EMT- and CSC-like phenotype [ 32– 32].

Breast tumors are stiffer and more hypoxic than nonmalignant breast tissue.

The air coming through the mask was even more hypoxic, like the air at twenty-one thousand feet.

The aggressive hypoxic phenotype of neuroblastoma is well documented.

Moreover, our signature might be refined to become a marker of this aggressive hypoxic phenotype.

The hypoxic phenotype of MM cells was shown to be reversible after reoxygenation.

This suggests involvement of the actin cytoskeleton a key determinant of cellular morphology in the hypoxic phenotype.

Interestingly, we showed that P-cadherin is associated to the hypoxic phenotype and metabolic reprogramming of breast cancer cells.